Ketamine for depression: A collection of key papers
This collection of papers is posted here to make them easily accessible for psychiatrists considering this form of treatment.
Dr David Straton. MBChB, DPM, FRANZCP.
Effect Offers Drug-Development Target
New Targets for Treatment:
Current Research at the NIMH Mood and Anxiety Disorders Program.
Ketamine and NMDA Receptor Antagonists for Depression
Could a drug prevent depression and PTSD?
A Consensus Statement on the Use of Ketamine
in the Treatment of Mood Disorders
Use of Ketamine in Clinical Practice:
A Time for Optimism and Caution
Ketamine and Rapid-Acting Antidepressants: A Window into a New Neurobiology for Mood Disorder Therapeutics
A systematic review and meta-analysis of randomized, double-blind, placebo-controlled trials
of ketamine in the rapid treatment of major depressive episodes
Off-label use of transmucosal ketamine as a rapid-acting antidepressant: a retrospective chart review
A Randomized Controlled Trial of Intranasal Ketamine in Major Depressive Disorder
Oral ketamine augmentation for chronic suicidality in treatment-resistant depression
Ketamine as a new treatment for depression: A review of its efficacy and
Antidepressant, mood stabilizing and
procognitive effects of very low dose
sublingual ketamine in refractory unipolar and bipolar depression.
Sublingual ketamine in chronic pain: service evaluation by examining more than 200 patient years
Daily Oral Ketamine for the Treatment of Depression
and Anxiety in Patients Receiving Hospice Care: A 28-Day Open-Label Proof-of-Concept Trial
Oral Ketamine for the Rapid Treatment of Depression and Anxiety in Patients Receiving Hospice Care
Two Case Studies of Patients with Major Depressive Disorder Given Low-Dose (Subanesthetic) Ketamine Infusions. Correll GE and Futter GE. Pain Medicine. 7, 1. 2006. Pdf .
A Randomized Trial of an N-methyl-D-aspartate Antagonist in Treatment-Resistant Major Depression. Carlos A. Zarate, et al. Arch Gen Psychiatry. 2006;63:856-864. Pdf
therapy in a patient with a treatment-resistant major depression
Antidepressant Effect of Ketamine During ECT
of ketamine in depressed patients
NMDA receptor antagonists ketamine and Ro25-6981 inhibit evoked release of glutamate in vivo in the subiculum
Synaptic Dysfunction in Depression:
Potential Therapeutic Targets
Targeting the glutamatergic system to develop
novel, improved therapeutics for mood disorders
Psychiatric safety of ketamine in psychopharmacology research
Subanesthetic ketamine: how it alters physiology and behavior
Clinical studies implementing glutamate neurotransmission in
Glutamate and psychiatric disorders
Long-term outcome of patients who receive ketamine during research
More references on Ketamine, Glutamate and Depression
Subanesthetic Ketamine Infusion Therapy: A Retrospective Analysis
of a Novel Therapeutic Approach to Complex Regional Pain Syndrome
Ketamine in Chronic
Pain Management: An Evidence-Based Review
The role of Ketamine in the management of chronic pain
Safety and Efficacy of Prolonged Outpatient Ketamine Infusions
for Neuropathic Pain.
Ketalar Data Sheet
Access to Unapproved
Therapeutic Goods in Australia
Niki T34 Syringe pump
A review of the non-medical
use of ketamine: part 1: use, users and consequences.